Lymphoangiocrine signals promote cardiac growth and repair
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چکیده
منابع مشابه
Wnt1/bcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair
Jinzhu Duan, Costin Gherghe, Dianxin Liu, Eric Hamlett, Luxman Srikantha, Laurel Rodgers, Jenna N Regan, Mauricio Rojas, Monte Willis, Andrew Leask, Mark Majesky and Arjun Deb* Department of Medicine, McAllister Heart Institute and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA, Department of Cell and Molecular Physiology, McAllister Heart Institute a...
متن کاملWnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair.
Wnts are required for cardiogenesis but the role of specific Wnts in cardiac repair remains unknown. In this report, we show that a dynamic Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair. Acute ischaemic cardiac injury upregulates Wnt1 that is initially expressed in the epicardium and subsequently by cardiac fibroblasts in the region of ...
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Hsia, Connie C. W. Signals and mechanisms of compensatory lung growth. J Appl Physiol 97: 1992–1998, 2004; doi:10.1152/japplphysiol.00530.2004.— Growth of the lung involves unique structure-function interactions not seen in solid organs. Mechanical feedback between the lung and thorax constitutes a major signal that sustains developmental as well as compensatory lung growth. After the loss of l...
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ژورنال
عنوان ژورنال: Nature
سال: 2020
ISSN: 0028-0836,1476-4687
DOI: 10.1038/s41586-020-2998-x